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valdecoxib
Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms. It is a cyclooxygenase-2 selective inhibitor.
Valdecoxib was manufactured and marketed under the brand name Bextra by G. D. Searle & Company. It was approved by the United States Food and Drug Administration on November 20, 2001,〔Thomson Micromedex. ("Valdecoxib. U.S. FDA Drug Approval." ) Last accessed June 8, 2007.〕 and was available by prescription in tablet form until 2005, when it was removed from the market due to concerns about possible increased risk of heart attack and stroke. The prodrug parecoxib is available in many countries.
==Uses until 2005==
In the United States, the Food and Drug Administration (FDA) approved valdecoxib for the treatment of osteoarthritis, adult rheumatoid arthritis, and primary dysmenorrhea.〔(【引用サイトリンク】 Pfizer to pay $2.3 billion to resolve criminal and civil health care liability relating to fraudulent marketing and the payment of kickbacks )〕
Valdecoxib was also used off-label for controlling acute pain and various types of surgical pain.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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