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vanillotoxin
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Vanillotoxins (VaTxs, subtypes VaTx1, VaTx2, and VaTx3) are neurotoxins found in the venom of the tarantula ''Psalmopoeus cambridgei''. They act as agonists for the transient receptor potential cation channel subfamily V member 1 (TRPV1), activating the pain sensory system. VaTx1 and 2 also act as antagonists for the Kv2-type voltage-gated potassium channel (Kv2), inducing paralytic behavior in small animals.〔
== Origin ==
''P. cambridgei'', a tarantula from Trinidad, uses its venom to paralyze its prey. Amongst other compounds, this venom contains all three subtypes of VaTxs: VaTx1, VaTx2, and VaTx3.〔
The name of the toxin was derived from the vanilloid receptor TRPV1, to which the VaTxs bind.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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