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verapamil
Verapamil (INN) (sold under various trade names) is an L-type calcium channel blocker of the phenylalkylamine class. It has been used in the treatment of hypertension, angina pectoris, cardiac arrhythmia, and most recently, cluster headaches. It is also an effective preventive medication for migraine. Verapamil has also been used as a vasodilator during cryopreservation of blood vessels. It is a class-IV antiarrhythmic, more effective than digoxin in controlling ventricular rate and was approved by the U.S. Food and Drug Administration (FDA) in March 1982.〔(【引用サイトリンク】work=MedicineNet.com )〕
It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.
==Medical uses==
Verapamil is also used intra-arterially to treat cerebral vasospasm. Verapamil has been used to treat cluster headaches, but it also lists headaches as a side effect of the drug.〔 Verapamil is used for controlling ventricular rate in supraventricular tachycardia and migraine headache prevention. Verapamil is not listed as a first line agent by the guidelines provided by JAMA in JNC-8. However, it may be used to treat hypertension if patient has co-morbid atrial fibrillation or other types of arrhythmia.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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