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vicine : ウィキペディア英語版
vicine

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Vicine is an alkaloid glycoside found in fava beans.〔Variability of Amino Acids, Protein, Vicine and Convicine in Vicia faba (L) Cultivars. Vincenzo Lattanzio, Vito V. Bianco, Giuseppe Crivelli and Vito Miccolis, Journal of Food Science, Volume 48, Issue 3, pages 992–993, May 1983 〕 Vicine is toxic, causing the disease favism, in individuals who have a hereditary loss of the enzyme glucose-6-phosphate dehydrogenase. Divicine is the name of the aglycone of vicine. Fava beans also contain the related 6-hydroxy- alkaloid glycoside covicine, whose aglycone is isouramil.
Vicine was first isolated by Heinrich Ritthausen. Classified as a pyrimidine, its structure and that of divicine has been described.〔Aaron Bendich & Grace C. Clements (1953) "A revision to the structural formation of vicine and its pyrimidine aglucone, divicine", Biochimica et Biophysica Acta〕 The formation in Vicia Faba of vicine and covicine has been investigated.〔E. G. Brown & F. M. Roberts (1972) "Formation of Vicine and Covicine by ''Vicia Faba''", Phytochemistry 11:3203–6〕
== References ==


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