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vicryl
Vicryl (polyglactin 910) is an absorbable, synthetic, usually braided suture, manufactured by Ethicon Inc., a subsidiary of Johnson and Johnson. A monofilament version is also made for use in ophthalmic practice. It is indicated for soft tissue approximation and ligation. The suture holds its tensile strength for approximately two to three weeks in tissue, and is completely absorbed by hydrolysis within 56–70 days.〔http://www.ethicon.com/healthcare-professionals/products/wound-closure/coated-vicryl-polyglactin-910-suture#!description-and-specs〕 Vicryl and other polyglycolic-acid sutures may also be treated for more rapid breakdown ("Vicryl Rapide") in rapidly healing tissues such as mucous membrane, or impregnated with triclosan ("Vicryl Plus Antibacterial") to provide antimicrobial protection of the suture line. Because vicryl is slow-absorbing and often braided, its use is contraindicated in closure of any cutaneous wound exposed to the air, as it draws moisture from the healing tissue to the skin and allows bacteria and irritants to migrate into the wound. This inevitably leads to high reactivity to the contaminants, poor wound healing, and eventually infection. 〔http://www.ncbi.nlm.nih.gov/pubmed/24418453〕
Although the name "Vicryl" is a trademark of Ethicon, the term "vicryl" has been used generically referring to any synthetic absorbable suture made primarily of polyglycolic acid. Other brands of polyglycolic acid suture include Surgicryl, Polysorb and Dexon, all of which are manufactured by different companies.
vicryl can be multifilament , it is a copolymer of lactide ( a cyclic di-ester of lactic acid ) and glycoside , in practice , vicryl comes as braided , dyed and undyed with the following decay schedule , 75 % at 2 weeks , 50 % at 3 weeks and 25% at 4 weeks with average absorption time of 2 weeks .
==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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