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vinblastine
Vinblastine is a medication used to treat a number of types of cancer including: Hodgkin's lymphoma, non-small cell lung cancer, bladder cancer, brain cancer, and testicular cancer among others.〔(【引用サイトリンク】 url=http://www.drugs.com/monograph/vinblastine-sulfate.html )〕 It is used intravenously and works by inhibiting mitosis.〔
Most people experience some side effects.〔 Commonly it causes a change in sensation, constipation, weakness, loss of appetite, and headaches among other symptoms.〔 It will likely cause harm to an infant if given during pregnancy.〔
The isolation of vinblastine was first reported in 1958. It is on the World Health Organization's List of Essential Medicines, the most important medication needed in a basic health system. As of 2014 the wholesale cost is between 7.70 and 31.70 USD per dose.〔(【引用サイトリンク】url=http://erc.msh.org/dmpguide/resultsdetail.cfm?language=english&code=VINB10I&s_year=2014&year=2014&str=10%20mg&desc=Vinblastine&pack=new&frm=VIAL&rte=INJ&class_code2=08%2E2%2E&supplement=&class_name=%2808%2E2%2E%29Cytotoxic%20and%20adjuvant%20medicines%3Cbr%3E )〕 Vinblastine was traditionally obtained from ''Catharanthus roseus'', also known as ''Vinca rosea'', a Madagascar Periwinkle. It is generated in the plant by the joining of two alkaloids catharanthine and vindoline.
== Medical uses ==
Vinblastine is a component of a number of chemotherapy regimens, including ABVD for Hodgkin lymphoma. It is also used to treat histiocytosis according to the established protocols of the Histiocytosis Association.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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