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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク 10-Formyltetrahydrofolate ： ウィキペディア英語版 10-Formyltetrahydrofolate |Section2= |Section3= }} 10-Formyltetrahydrofolate (10-CHO-THF) is a form of tetrahydrofolate that acts as a donor of formyl groups in anabolism. In these reactions 10-CHO-THF is used as a substrate in formyltransferase reactions. This is important in purine biosynthesis, where 10-CHO-THF is a substrate for phosphoribosylaminoimidazolecarboxamide formyltransferase, as well as in the formylation of the methionyl initiator tRNA (fMet-tRNA), when 10-CHO-THF is a substrate for methionyl-tRNA formyltransferase. ==Biosynthesis== 10-CHO-THF is produced either by the enzyme methenyltetrahydrofolate cyclohydrolase via the reaction :5,10-methenyltetrahydrofolate + H2O $\backslash rightleftharpoons$ 10-formyltetrahydrofolate or by the enzyme formate-tetrahydrofolate ligase via the reaction :ATP + formate + tetrahydrofolate $\backslash rightleftharpoons$ ADP + phosphate + 10-formyltetrahydrofolate It can be converted back into tetrahydrofolate (THF) by formyltetrahydrofolate dehydrogenase or THF and formate by formyltetrahydrofolate deformylase. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「10-Formyltetrahydrofolate」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.